With the development of novel systemic therapies and treatment approaches and technological sophistication, cancer care is no longer one size fits all. With the integrated efforts of radiation oncologists, medical oncologists, surgical oncologists, and palliative care physicians incorporating information provided by radiologists, pathologists, and medical physicists, the most optimal personalized cancer care can be rendered. The American Radium Society (ARS) promotes the study of cancer and integrated personalized cancer care. ARS Annual Meeting encourages liaison among the various medical specialists and allied scientists who are looking after patients with cancer. ARS supports scientific study of the treatment of cancer patients through its annual meeting scientific program and educational publications. The goal of the ARS 2025 Annual Meeting is to provide a highly inclusive, engaging, impactful, interactive, and educational meeting for a broad group of learners, including physicians, medical physicists, cancer scientists, advanced practice providers, trainees, and students. The conference will include a variety of learning formats to facilitate interprofessional interactions and discussions and dissemination of knowledge from presenters to participants.